Intestinal adaptation and Reg gene expression induced by anti-diabetic duodenal-jejunal
نویسنده
چکیده
AJP-GI Liver 1/20/2013 1 Intestinal adaptation and Reg gene expression induced by anti-diabetic duodenal-jejunal 2 bypass surgery in Zucker fatty rats 3 4 5 Bing Li, Yarong Lu, CB Srikant, Zu-Hua Gao, Jun-Li Liu 6 7 Fraser Laboratories for Diabetes Research, Department of Medicine, McGill University Health 8 Centre, Montreal, Canada; Department of Pathology, McGill University Health Centre; 9 Montreal Diabetes Research Centre, Montreal, Canada (*These authors have contributed 10 equally) 11 12 Running head: Intestinal adaptation to duodenal-jejunal bypass 13 14 Correspondence: Dr. Jun-Li Liu, Fraser Laboratories, Room H5.21, Royal Victoria Hospital, 15 687 Pine Avenue West, Montreal, QC H3A 1A1, Canada. Email: [email protected]; 16 Phone: (514) 934-1934 Ext 35059 17 18
منابع مشابه
Intestinal adaptation and Reg gene expression induced by antidiabetic duodenal-jejunal bypass surgery in Zucker fatty rats.
The antidiabetic mechanism of bariatric surgery includes specific changes in the secretion of incretins. To identify additional players originating from the gut, we evaluated the effects of duodenal-jejunal bypass (DJB) in morbidly obese Zucker fatty rats. A fast relief of hyperglycemia and hyperinsulinemia was achieved even before a significant weight loss occurred. Fourteen days after DJB, we...
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